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BrainCells Inc. (BCI), a
biopharmaceutical company utilizing its platform technology to identify and
develop compounds that promote the growth of new neurons for the treatment
of central nervous system (CNS) diseases, announced that it has
initiated a Phase 2a clinical trial with its lead product candidate,
BCI-540, for the treatment of depression with anxiety.
"We are encouraged by the enthusiasm expressed by our clinical
investigators who view BCI-540 as a potential alternative to today’s widely
prescribed treatments for depression," noted Carrolee Barlow, M.D., Ph.D.,
Chief Scientific Officer at BCI. "Current therapies directly impact
serotonin levels causing many unpleasant side effects, however we have
shown that BCI-540 directly impacts neurogenesis without affecting
serotonin levels. We are excited about the potential of this compound to
change the way mood disorders are treated."
The twelve-week randomized double-blind, placebo-controlled study will
evaluate safety, efficacy and tolerability of BCI-540 to determine whether
80 mg given once or three times daily is effective in the treatment of
depression with anxiety versus placebo.
"BCI is utilizing our understanding of the power of neurogenesis
coupled with our proprietary neurogenic platform technology to identify a
strong portfolio of clinical candidates, such as BCI-540, that we plan to
move into the clinic this year," said Jim Schoeneck, CEO at BCI. "Moving
BCI-540 into the clinic is an important milestone and we are now actively
enrolling patients and anticipate completing enrollment by the end of this
year."
Buy zithromax pills About BrainCells Inc.
BrainCells Inc. (BCI) is a San Diego-based drug discovery and
development company that is applying its proprietary neurogenesis platform
technology to identify and reposition compounds for the treatment of
central nervous system (CNS) diseases. Neurogenesis is the process by which
endogenous stem cells in the adult human brain produce new brain tissue,
including neurons. With its predictive screening platform, BCI can direct
the selection and development of neurogenic compounds, increasing the
opportunity for successful clinical trials in a variety of CNS indications.
For more information, visit
BrainCells Inc.

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